Israel said their latest joint strikes with the U.S. dealt major damage to Iran’s military command structure, as the Washington announced it had destroyed the headquarters of Iran's powerful Revolutionary Guards.

Prime Minister Benjamin Netanyahu vowed that air strikes on Tehran will intensify in the coming days while President Donald Trump said he be talking to Iranian leaders, without specifying a timeline.

The European Union meanwhile warned the Middle East region "stands to lose greatly" from a long war, after an emergency meeting of the 27-nation bloc's foreign ministers.

Powerful explosions rocked the Iranian capital on the second day of the war, with media reports that people were trapped under the rubble of a police station.

The Israeli military said it had dealt a "severe blow" to Iran's command and control centers after a fresh wave of strikes on military targets in the Islamic republic.

The military said it "struck dozens of the regime's military command centers, including headquarters belonging to the Islamic Revolutionary Guard Corps (IRGC), intelligence headquarters, IRGC Air Force command centers, and internal security headquarters".

The U.S. military announced it had destroyed the IRGC headquarters.

"America has the most powerful military on earth, and the IRGC no longer has a headquarters," the US Central Command, or CENTCOM, said in a statement, adding that the strike had occurred on Saturday.